Protein secondary structure prediction based on position-specific scoring matrices.

  title={Protein secondary structure prediction based on position-specific scoring matrices.},
  author={D. T. Jones},
  journal={Journal of molecular biology},
  volume={292 2},
  • D. T. Jones
  • Published 17 September 1999
  • Computer Science
  • Journal of molecular biology
A two-stage neural network has been used to predict protein secondary structure based on the position specific scoring matrices generated by PSI-BLAST. Despite the simplicity and convenience of the approach used, the results are found to be superior to those produced by other methods, including the popular PHD method according to our own benchmarking results and the results from the recent Critical Assessment of Techniques for Protein Structure Prediction experiment (CASP3), where the method… 

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