Protein release from gelatin matrices.

  title={Protein release from gelatin matrices.},
  author={Ikada and Tabata},
  journal={Advanced drug delivery reviews},
  volume={31 3},
  • Ikada, Tabata
  • Published 1998 in Advanced drug delivery reviews
Gelatin is a denatured, biodegradable protein obtained by acid and alkaline processing of collagen. This processing affects the electrical nature of collagen, yielding gelatin with different isoelectric points (IEPs). When mixed with positively or negatively charged gelatin, an oppositely charged protein will ionically interact to form a polyion complex. This review article describes protein release from charged gelatin matrices on the basis of this polyion complexation. The biodegradable… CONTINUE READING