Protein-rejecting ability of surface-bound dextran in end-on and side-on configurations: comparison to PEG.

@article{Osterberg1995ProteinrejectingAO,
  title={Protein-rejecting ability of surface-bound dextran in end-on and side-on configurations: comparison to PEG.},
  author={E Osterberg and Katrin Bergstr{\"o}m and Krister Holmberg and Thomas P. Schuman and J A Riggs and Natasha Burns and James M Van Alstine and Jonathan M Harris},
  journal={Journal of biomedical materials research},
  year={1995},
  volume={29 6},
  pages={741-7}
}
There is much interest in attaching polyethylene glycol (PEG) and other hydrophilic, neutral polymers to surfaces to reduce the extent of protein and cell adsorption. Interestingly, these same surface-bound polymers are effective in masking surface charge and reducing electrokinetic effects such as particle electrophoretic mobility, streaming potential, and electroosmosis. It is apparent that similar molecular properties are responsible for both protein and cell rejection and reduction of… CONTINUE READING

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