Protein redox chemistry: post-translational cysteine modifications that regulate signal transduction and drug pharmacology


The perception of reactive oxygen species has evolved over the past decade from agents of cellular damage to secondary messengers which modify signaling proteins in physiology and the disease state (e.g., cancer). New protein targets of specific oxidation are rapidly being identified. One emerging class of redox modification occurs to the thiol side chain… (More)
DOI: 10.3389/fphar.2014.00224


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