Protein-protein interaction map for yeast TFIID.

  title={Protein-protein interaction map for yeast TFIID.},
  author={Gayatri Yatherajam and Lei Zhang and Susan M Kraemer and Laurie A. Stargell},
  journal={Nucleic acids research},
  volume={31 4},
A major rate-limiting step in transcription initiation by RNA polymerase II is recognition and binding of the TATA element by the transcription factor TFIID. TFIID is composed of TATA binding protein (TBP) and approximately a dozen TBP-associated factors (TAFs). Emerging consensus regarding the role of TAFs is that TFIID assumes a gene specific activity that is regulated by interaction with other factors. In spite of many studies demonstrating the essential nature of TAFs in transcription, very… CONTINUE READING


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