Protein-protein docking dealing with the unknown

@article{Moreira2010ProteinproteinDD,
  title={Protein-protein docking dealing with the unknown},
  author={Irina S. Moreira and Pedro Alexandrino Fernandes and Maria Jo{\~a}o Ramos},
  journal={Journal of computational chemistry},
  year={2010},
  volume={31 2},
  pages={317-42}
}
Protein-protein binding is one of the critical events in biology, and knowledge of proteic complexes three-dimensional structures is of fundamental importance for the biochemical study of pharmacologic compounds. In the past two decades there was an emergence of a large variety of algorithms designed to predict the structures of protein-protein complexes--a procedure named docking. Computational methods, if accurate and reliable, could play an important role, both to infer functional properties… CONTINUE READING

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