Protein post-translational modifications and regulation of pluripotency in human stem cells

@inproceedings{Wang2014ProteinPM,
  title={Protein post-translational modifications and regulation of pluripotency in human stem cells},
  author={Yu-Chieh Wang and Suzanne E. Peterson and Jeanne F Loring},
  booktitle={Cell Research},
  year={2014}
}
Post-translational modifications (PTMs) are known to be essential mechanisms used by eukaryotic cells to diversify their protein functions and dynamically coordinate their signaling networks. Defects in PTMs have been linked to numerous developmental disorders and human diseases, highlighting the importance of PTMs in maintaining normal cellular states. Human pluripotent stem cells (hPSCs), including embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), are capable of self… CONTINUE READING
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