Protein phosphorylation and taurine biosynthesis in vivo and in vitro.

  title={Protein phosphorylation and taurine biosynthesis in vivo and in vitro.},
  author={X. W. Tang and Chih Chao Hsu and John V. Schloss and Morris D Faiman and Eleanor Wu and Chao-yuh Yang and J. Y. Wu},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={17 18},
Taurine is known to be involved in many important physiological functions. Here we report that both in vivo and in vitro the taurine-synthesizing enzyme in the brain, namely cysteine sulfinic acid decarboxylase (CSAD), is activated when phosphorylated and inhibited when dephosphorylated. Furthermore, protein kinase C and protein phosphatase 2C have been identified as the enzymes responsible for phosphorylation and dephosphorylation of CSAD, respectively. In addition, the effect of neuronal… CONTINUE READING


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