Protein phosphorylation and regulation of adaptive responses in bacteria.

  title={Protein phosphorylation and regulation of adaptive responses in bacteria.},
  author={Jeffry B. Stock and Alexander J. Ninfa and Ann M Stock},
  journal={Microbiological reviews},
  volume={53 4},
Bacteria continuously adapt to changes in their environment. Responses are largely controlled by signal transduction systems that contain two central enzymatic components, a protein kinase that uses adenosine triphosphate to phosphorylate itself at a histidine residue and a response regulator that accepts phosphoryl groups from the kinase. This conserved phosphotransfer chemistry is found in a wide range of bacterial species and operates in diverse systems to provide different regulatory… CONTINUE READING
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