Protein phosphatase 2A dysfunction in Alzheimer’s disease

@inproceedings{Sontag2014ProteinP2,
  title={Protein phosphatase 2A dysfunction in Alzheimer’s disease},
  author={J. -M. Sontag and Estelle Sontag},
  booktitle={Front. Mol. Neurosci.},
  year={2014}
}
Protein phosphatase 2A (PP2A) is a large family of enzymes that account for the majority of brain Ser/Thr phosphatase activity. While PP2A enzymes collectively modulate most cellular processes, sophisticated regulatory mechanisms are ultimately responsible for ensuring isoform-specific substrate specificity. Of particular interest to the Alzheimer's disease (AD) field, alterations in PP2A regulators and PP2A catalytic activity, subunit expression, methylation and/or phosphorylation, have been… CONTINUE READING
42 Citations
105 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 105 references

Involvement of I2PP2A

  • S. Khatoon, I. G. Iqbal, K. Iqbal
  • 2006
Highly Influential
8 Excerpts

From promiscuity to preci

  • S. Shenolikar
  • 2009
Highly Influential
1 Excerpt

Similar Papers

Loading similar papers…