Protein phosphatase 1 is a key player in nuclear events.

  title={Protein phosphatase 1 is a key player in nuclear events.},
  author={Sandra Rebelo and Mariana Sanches Santos and Filipa M. S. Martins and Edgar F. da Cruz e Silva and Odete A. B. da Cruz e Silva},
  journal={Cellular signalling},
  volume={27 12},
Reversible protein phosphorylation at serine (Ser), threonine (Thr) and tyrosine (Tyr) residues is among the major regulatory mechanism in eukaryotic cells. The eukaryotic genome encodes many protein kinases and protein phosphatases. However, the localization, activity and specificity towards phosphatase substrates are dictated by a large array of phosphatase binding and regulatory subunits. For protein phosphatase 1 (PP1) more than 200 binding subunits have been described. The various PP1… CONTINUE READING
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