Protein oxidative damage in arsenic induced rat brain: influence of DL-alpha-lipoic acid.

@article{Samuel2005ProteinOD,
  title={Protein oxidative damage in arsenic induced rat brain: influence of DL-alpha-lipoic acid.},
  author={Shila Samuel and R. Kathirvel and Tamilselvan Jayavelu and Panneerselvam Chinnakkannu},
  journal={Toxicology letters},
  year={2005},
  volume={155 1},
  pages={27-34}
}
A body of evidence has accumulated implicating free radical generation and reaction of arsenic with protein thiols in the biochemical and molecular mechanisms of arsenic toxicity. Brain readily undergoes oxidative damage, so it is important to determine whether arsenic-induced changes in rat brain may be associated with oxidative events. An increase in… CONTINUE READING