Protein nitration as footprint of oxidative stress-related nitric oxide signaling pathways in developing Ciona intestinalis.


Developmental processes in the ascidian Ciona intestinalis depend on a complex interplay of events including, during metamorphosis, a caspase-dependent apoptosis which is regulated by the nitric oxide (NO)-cGMP signaling pathway. Herein we disclose an alternate NO-mediated signaling pathway during Ciona development which appears to be critically dependent… (More)
DOI: 10.1016/j.niox.2012.03.012