Protein nanoparticles as drug carriers in clinical medicine.

@article{Hawkins2008ProteinNA,
  title={Protein nanoparticles as drug carriers in clinical medicine.},
  author={Michael Joel Hawkins and Patrick Soon-Shiong and N. Irav Desai},
  journal={Advanced drug delivery reviews},
  year={2008},
  volume={60 8},
  pages={
          876-85
        }
}
Solvent-based delivery vehicles for chemotherapy agents have been instrumental in providing a means for hydrophobic agents to be administered intravenously. These solvents, however, have been associated with serious and dose-limiting toxicities. Solvent-based formulations of taxanes, a highly active class of cytotoxic agents, are associated with hypersensitivity reactions, neutropenia, and neuropathy. Nanoparticle technology utilizing the human protein albumin exploits natural pathways to… CONTINUE READING
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