Protein modification in aging: an update.

  title={Protein modification in aging: an update.},
  author={Christian Sch{\"o}neich},
  journal={Experimental gerontology},
  volume={41 9},
Post-translational modifications of proteins are an important biologic tool for the production of various protein species from a single gene, which may vary in conformation, function, biologic half-life and complex formation with other proteins. The present minireview summarizes a few selected research observations important for the role of post-translational modifications in biologic aging and age-related diseases, including farnesylation, methylglyoxal-derivatization, transglutaminase… CONTINUE READING