Protein-mediated transformation of lipid vesicles into tubular networks.

@article{Simunovic2013ProteinmediatedTO,
  title={Protein-mediated transformation of lipid vesicles into tubular networks.},
  author={Mijo Simunovic and Carsten Mim and Thomas C Marlovits and Guenter P. Resch and Vinzenz Unger and Gregory A. Voth},
  journal={Biophysical journal},
  year={2013},
  volume={105 3},
  pages={
          711-9
        }
}
Key cellular processes are frequently accompanied by protein-facilitated shape changes in the plasma membrane. N-BAR-domain protein modules generate curvature by means of complex interactions with the membrane surface. The way they assemble and the mechanism by which they operate are largely dependent on their binding density. Although the mechanism at lower densities has recently begun to emerge, how membrane scaffolds form at high densities remains unclear. By combining electron microscopy… CONTINUE READING

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VIEW 2 EXCERPTS
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References

Publications referenced by this paper.
SHOWING 1-10 OF 45 REFERENCES

Nature of curvature coupling of amphiphysin with membranes depends on its bound density.

VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Structural basis of membrane bending by the N-BAR protein endophilin

  • C. Mim, H. Cui, V. M. Unger
  • 2012
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

New insights into BAR domain-induced membrane remodeling

  • G. S. Ayton, E. Lyman, G. A. Voth
  • Biophys. J. 97:1616–1625
  • 2009
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Membrane curvature and mechanisms of dynamic cell membrane remodelling

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Molecular Biology of the Cell, 4th ed

  • B. Alberts
  • 2002
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

A Hybrid Approach for Highly Coarse-grained Lipid Bilayer Models.

VIEW 1 EXCERPT

Understanding the role of amphipathic helices in N-BAR domain driven membrane remodeling

  • H. Cui, C. Mim, G. A. Voth
  • Biophys. J. 104:404–411
  • 2013
VIEW 1 EXCERPT