Protein-mediated molecular bridging: a key mechanism in biopolymer organization.

Abstract

Protein-mediated bridging is ubiquitous and essential for shaping cellular structures in all organisms. Here we dissect this mechanism for a model system: the Histone-like Nucleoid-Structuring protein (H-NS). We present data from two complementary single-molecule assays that probe the H-NS-DNA interaction: a dynamic optical-trap-driven unzipping assay and… (More)
DOI: 10.1016/j.bpj.2009.06.051

Topics

4 Figures and Tables