Protein material costs: single atoms can make an evolutionary difference.

@article{Bragg2009ProteinMC,
  title={Protein material costs: single atoms can make an evolutionary difference.},
  author={Jason G Bragg and Andreas Wagner},
  journal={Trends in genetics : TIG},
  year={2009},
  volume={25 1},
  pages={5-8}
}
The process of gene expression has material costs caused by the quantities of carbon, nitrogen, sulfur and phosphorus that are needed to make mRNAs and proteins. When any such chemical element is ecologically limiting, mutations increasing these costs can reduce growth. Here, we ask if such mutations are 'visible' to natural selection in the yeast… CONTINUE READING