Protein lysine acylation and cysteine succination by intermediates of energy metabolism.

  title={Protein lysine acylation and cysteine succination by intermediates of energy metabolism.},
  author={Hening Lin and Xiaoyang Su and Bin He},
  journal={ACS chemical biology},
  volume={7 6},
In the past few years, several new protein post-translational modifications that use intermediates in metabolism have been discovered. These include various acyl lysine modifications (formylation, propionylation, butyrylation, crotonylation, malonylation, succinylation, myristoylation) and cysteine succination. Here, we review the discovery and the current understanding of these modifications. Several of these modifications are regulated by the deacylases, sirtuins, which use nicotinamide… CONTINUE READING
51 Extracted Citations
103 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 51 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 103 references

Bioorthogonal proteomics of 15hexadecynyloxyacetic acid chemical reporter reveals preferential targeting of fatty acid modi fi ed proteins and biosynthetic enzymes

  • B. R. Martin, B. F. Cravatt
  • Bioorg . Med . Chem .
  • 2012

Identi fi cation of a molecular component of the mitochondrial acetyl transferase program ; a novel role for GCN 5 L 1

  • H. Xu, S. S. Hegde, J. S. Blanchard
  • Biochem J .
  • 2012

Aberrant succination of proteins in fumarate hydratasede fi cient mice and HLRCC patients is a robust biomarker of mutation status

  • N. F. Villeneuve, A. Lau, D. D. Zhang
  • J . Pathol .
  • 2011

Similar Papers

Loading similar papers…