Protein lysine acylation and cysteine succination by intermediates of energy metabolism.

@article{Lin2012ProteinLA,
  title={Protein lysine acylation and cysteine succination by intermediates of energy metabolism.},
  author={Hening Lin and Xiaoyang Su and Bin He},
  journal={ACS chemical biology},
  year={2012},
  volume={7 6},
  pages={947-60}
}
In the past few years, several new protein post-translational modifications that use intermediates in metabolism have been discovered. These include various acyl lysine modifications (formylation, propionylation, butyrylation, crotonylation, malonylation, succinylation, myristoylation) and cysteine succination. Here, we review the discovery and the current understanding of these modifications. Several of these modifications are regulated by the deacylases, sirtuins, which use nicotinamide… CONTINUE READING
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