Protein-losing enteropathy associated with Clostridium difficile infection.

@article{Rybolt1989ProteinlosingEA,
  title={Protein-losing enteropathy associated with Clostridium difficile infection.},
  author={A H Rybolt and Richard Gary Bennett and B E Laughon and David R Thomas and William B. Greenough and John G. Bartlett},
  journal={Lancet},
  year={1989},
  volume={1 8651},
  pages={1353-5}
}
A commercially available radial immunodiffusion assay was used to measure serum alpha-1-antitrypsin levels in stool samples from subjects aged over 60 years as a marker of protein-losing enteropathy. alpha 1-antitrypsin was found in all of 12 patients with colonoscopy-confirmed pseudomembranous colitis, 6 of 14 (43%) patients with Clostridium difficile diarrhoea without pseudomembranes, 6 of 12 (50%) nursing-home patients culture-positive for Cl difficile but negative for its cytotoxin, and… CONTINUE READING

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