Protein-losing Enteropathy Caused by Intestinal or Colonic Lymphangiectasia Complicated by Sporadic Lymphangioleiomyomatosis: A Report of Two Cases

@inproceedings{Nishino2017ProteinlosingEC,
  title={Protein-losing Enteropathy Caused by Intestinal or Colonic Lymphangiectasia Complicated by Sporadic Lymphangioleiomyomatosis: A Report of Two Cases},
  author={Koichi Nishino and Kaku Yoshimi and Tomoyoshi Shibuya and Takuo Hayashi and Keiko Mitani and Etsuko Kobayashi and Masako Ichikawa and Tetsuhiko Asao and Yohei Suzuki and Tadashi Sato and Satomi Shiota and Yuzo Kodama and Kazuhisa Takahashi and Kuniaki Seyama},
  booktitle={Internal medicine},
  year={2017}
}
This report describes two patients with sporadic lymphangioleiomyomatosis complicated by protein-losing enteropathy (PLE). Imaging studies indicated retroperitoneal lymphangioleiomyomas and abnormalities of the adjacent digestive tract. Endoscopic mucosal biopsy revealed colonic lymphangiectasia in one patient; whereas the site in the other patient was intestinal. Treatment with sirolimus led to the complete resolution of PLE within several months; additionally, marked shrinkage was observed in… CONTINUE READING