Protein kinases: which one is the memory molecule?

@article{Micheau1999ProteinKW,
  title={Protein kinases: which one is the memory molecule?},
  author={Jacques Micheau and Gernot Riedel},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={1999},
  volume={55},
  pages={534-548}
}
Encoding of new experiences is likely to induce activity-dependent modifications in the brain. Studies in organisms far apart on the phylogenetic scale have shown that similar, sometimes identical, signal transduction pathways subserve plasticity in neuronal systems, and they may play pivotal roles in the formation of long-term memories. It has become evident that phosphorylation/dephosphorylation reactions are critical for the initiation of cellular mechanisms that embody, retain and modify… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 121 references

Abnormal hippocampal spatial representations in a CaMKIIT 286 A and CREB a D − mice

  • H. ChoY., P. GieseK., H. Tanila, J. SilvaA.
  • Science
  • 1998

Nitric oxide synthase inhibitors impair reference memory formation in a radial arm maze task in rats

  • B. ZouL., K. Yamada, T. Tanaka, T. Kameyama, T Nabeshima
  • Neuropharmacology
  • 1998

Positive and negative regulatory mechanisms that mediate long - term memory stor

  • T. Abel, R. KandelE.
  • Brain Res . Rev .
  • 1998

Presynap - tic long - term depression at a central glutamatergic synapse : a role for CaMKII

  • W. MargrieT., P. RostasJ.A., P. Sah
  • Nature Neurosci
  • 1998