Protein kinase inhibitors can control the progression of endometriosis in vitro and in vivo.

@article{Ng2010ProteinKI,
  title={Protein kinase inhibitors can control the progression of endometriosis in vitro and in vivo.},
  author={Charlotte Ng{\^o} and Carole Nicco and Mahaut Leconte and Christiane Ch{\'e}reau and Sylviane Arkwright and Marie-C{\'e}cile Vacher-Lavenu and Bernard Weill and Charles Chapron and Fr{\'e}d{\'e}ric Batteux},
  journal={The Journal of pathology},
  year={2010},
  volume={222 2},
  pages={148-57}
}
Endometriosis affects 6-10% of women in their reproductive years, causing chronic pelvic pain and infertility. Its pathogenesis remains poorly understood and current treatments, based on hormonal therapy or surgery, are often insufficient. The purpose of our study was to investigate the role of the ERK pathway in the development of endometriosis and to test the effects of protein kinase inhibitors on the proliferation of endometriotic cells in vitro and in vivo. We studied ex vivo human… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Antiproliferative effects of anastrozole , methotrexate , and 5 - fluorouracil on endometriosis in vitro and in vivo

  • GL Johnson, R Lapadat
  • Fertil Steril
  • 2009

Similar Papers

Loading similar papers…