Protein kinase D1 promotes anchorage-independent growth, invasion, and angiogenesis by human pancreatic cancer cells.

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases. Novel molecularly targeted therapies are urgently needed. Here, we extended our studies on the role of protein kinase D1 (PKD1) in PDAC cell lines. Given that Panc-1 express moderate levels of PKD1, we used retroviral-mediated gene transfer to create a Panc-1 derivative that stably… (More)
DOI: 10.1002/jcp.22421

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@article{Ochi2011ProteinKD, title={Protein kinase D1 promotes anchorage-independent growth, invasion, and angiogenesis by human pancreatic cancer cells.}, author={Nubuo Ochi and Suebpong Tanasanvimon and Yoichi Matsuo and Zhimin Tong and Bokyung Sung and Bharat Bhushan Aggarwal and James Sinnett-Smith and Enrique Rozengurt and S. Guha}, journal={Journal of cellular physiology}, year={2011}, volume={226 4}, pages={1074-81} }