Protein kinase D-dependent trafficking of the large Herpes simplex virus type 1 capsids from the TGN to plasma membrane.

@article{RmillardLabrosse2009ProteinKD,
  title={Protein kinase D-dependent trafficking of the large Herpes simplex virus type 1 capsids from the TGN to plasma membrane.},
  author={Gaudeline R{\'e}millard-Labrosse and Constantina Mihai and Johanne Duron and Ginette Guay and Roger Lipp{\'e}},
  journal={Traffic},
  year={2009},
  volume={10 8},
  pages={1074-83}
}
The biosynthetic pathway carries cargos from the endoplasmic reticulum (ER) to the trans Golgi network (TGN) via a typical passage through the Golgi. Interestingly, large particles such as procollagen, chylomicrons and some viruses all reach the TGN by atypical routes. Given this dichotomy, we anticipated that such cargos might rely on non-classical machineries downstream of the TGN. Using Herpes simplex virus type 1 (HSV-1) as a model and a synchronized infection protocol that focuses on TGN… CONTINUE READING

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