Protein kinase C isozymes and substrates.

  title={Protein kinase C isozymes and substrates.},
  author={Susan Jaken},
  journal={Current opinion in cell biology},
  volume={8 2},
  • Susan Jaken
  • Published 1996 in Current opinion in cell biology
As most cells express more than one type of protein kinase C (PKC), it has been difficult to establish the role of individual PKCs in cellular functions. Isozyme differences in cofactor requirements and subcellular location, in addition to variability in expression of PKCs and substrates among various cell types, are all involved in determining the effects of PKC activation. Recent identification of cellular PKC-targeting proteins and of isozyme-selective functions has provided new insight into… CONTINUE READING
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