Protein kinase C isoforms in atherosclerosis: pro- or anti-inflammatory?

@article{Fan2014ProteinKC,
  title={Protein kinase C isoforms in atherosclerosis: pro- or anti-inflammatory?},
  author={Hueng-Chuen Fan and Carlos Fern{\'a}ndez-Hernando and Jenn-Haung Lai},
  journal={Biochemical pharmacology},
  year={2014},
  volume={88 2},
  pages={
          139-49
        }
}
Atherosclerosis is a pathologic condition caused by chronic inflammation in response to lipid deposition in the arterial wall. There are many known contributing factors such as long-term abnormal glucose levels, smoking, hypertension, and hyperlipidemia. Under the influence of such factors, immune and non-immune effectors cells are activated and participate during the progression of atherosclerosis. Protein kinase C (PKC) family isoforms are key players in the signal transduction pathways of… CONTINUE READING
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