Protein kinase C inhibition by calmodulin and its fragments.

Abstract

Inhibition of protein kinase C (PKC) by calmodulin is investigated and we describe the localization of inhibitory sequences within the calmodulin molecule. We present evidence that calmodulin inhibits PKC through an inhibition of the activation of PKC associated with lipid membranes: Binding of PKC to lipid vesicles is not affected, but activation is… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.