Protein kinase C activity and reactivity to phorbol ester in vascular smooth muscle from spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY).

@article{Silver1988ProteinKC,
  title={Protein kinase C activity and reactivity to phorbol ester in vascular smooth muscle from spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY).},
  author={Peter Silver and R E Lepore and Wayne R. Cumiskey and Daniel Kiefer and Adrian L. Harris},
  journal={Biochemical and biophysical research communications},
  year={1988},
  volume={154 1},
  pages={272-7}
}
Protein kinase C (PKC) activity in aortic and renal arterial smooth muscle from SHR (20-23 wk male; mean arterial pressure = 178 mm Hg) and WKY (age/sex matched; mean arterial pressure = 126 mm Hg) was quantitated. Activity was greatest in the particulate fractions relative to the soluble fractions in all sources. The only difference between SHR and WKY was… CONTINUE READING