Protein kinase C-β contributes to NADPH oxidase activation in neutrophils

@inproceedings{DekkerProteinKC,
  title={Protein kinase C-β contributes to NADPH oxidase activation in neutrophils},
  author={Lodewijk V Dekker and Michael Leitges and Gabriel M Altschuler and N Mistry and Aileen McDermott and Jurgen Roes and Anthony W Segal}
}
We have analysed the involvement of the β isotype of the protein kinase C (PKC) family in the activation of NADPH oxidase in primary neutrophils. Using immunofluorescence and cell fractionation, PKC-β is shown to be recruited to the plasma membrane upon stimulation with phorbol ester and to the phagosomal membrane upon phagocytosis of IgG-coated particles… CONTINUE READING