Protein kinase Cε induces systolic cardiac failure marked by exhausted inotropic reserve and intact Frank-Starling mechanism

  title={Protein kinase C$\epsilon$ induces systolic cardiac failure marked by exhausted inotropic reserve and intact Frank-Starling mechanism},
  author={David E. Montgomery and Veronica L. M. Rundell and Paul H. Goldspink and Dalia Urboniene and David L. Geenen and Pieter P. de Tombe and Peter Buttrick},
  journal={American Journal of Physiology-heart and Circulatory Physiology},
Myofilament dysfunction is a common point of convergence for many forms of heart failure. Recently, we showed that cardiac overexpression of PKCe initially depresses myofilament activity and then l... 

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