Protein kinase B (PKB/Akt)--a key regulator of glucose transport?

  title={Protein kinase B (PKB/Akt)--a key regulator of glucose transport?},
  author={Eric Hajduch and Gary J. Litherland and Harinder S Hundal},
  journal={FEBS letters},
  volume={492 3},
The serine/threonine kinase protein kinase B (PKB/Akt) has been shown to play a crucial role in the control of diverse and important cellular functions such as cell survival and glycogen metabolism. There is also convincing evidence that PKB plays a role in the insulin-mediated regulation of glucose transport. Furthermore, states of cellular insulin resistance have been shown to involve impaired PKB activation, and this usually coincides with a loss of glucose transport activation. However… CONTINUE READING


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