Protein kinase A regulates production of virulence determinants by the entomopathogenic fungus, Metarhizium anisopliae.

@article{Fang2009ProteinKA,
  title={Protein kinase A regulates production of virulence determinants by the entomopathogenic fungus, Metarhizium anisopliae.},
  author={Weiguo Fang and Monica Pava-ripoll and Sibao Wang and Raymond J St Leger},
  journal={Fungal genetics and biology : FG & B},
  year={2009},
  volume={46 3},
  pages={277-85}
}
Metarhizium anisopliae is a model system for studying insect fungal pathogenesis. The role of cAMP signal transduction in virulence was studied by disrupting the class I PKA catalytic subunit gene (MaPKA1). The PKA mutant (DeltaMaPKA1) showed reduced growth and greatly reduced virulence. PKA was dispensable for differentiation of infection structures (appressoria), but differentiation was delayed and the appressoria were defective because of reduced turgor pressure. DeltaMaPKA1 germinated at… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 45 extracted citations

Similar Papers

Loading similar papers…