Protein interaction verification and functional annotation by integrated analysis of genome-scale data.

@article{Kemmeren2002ProteinIV,
  title={Protein interaction verification and functional annotation by integrated analysis of genome-scale data.},
  author={Patrick Kemmeren and Nynke L. van Berkum and Jaak Vilo and Theo Bijma and Rogier Donders and Alvis Brazma and Frank Holstege},
  journal={Molecular cell},
  year={2002},
  volume={9 5},
  pages={1133-43}
}
Assays capable of determining the properties of thousands of genes in parallel present challenges with regard to accurate data processing and functional annotation. Collections of microarray expression data are applied here to assess the quality of different high-throughput protein interaction data sets. Significant differences are found. Confidence in 973 out of 5342 putative two-hybrid interactions from S. cerevisiae is increased. Besides verification, integration of expression and… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
126 Citations
48 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 126 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Similar Papers

Loading similar papers…