Protein interaction networks in medicine and disease.

  title={Protein interaction networks in medicine and disease.},
  author={I. W. F. Taylor and Jeffrey L. Wrana},
  volume={12 10},
The physical interaction of proteins is subject to intense investigation that has revealed that proteins are assembled into large densely connected networks. In this review, we will examine how signaling pathways can be combined to form higher order protein interaction networks. By using network graph theory, these interaction networks can be further analyzed for global organization, which has revealed unique aspects of the relationships between protein networks and complex biological… CONTINUE READING
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