Protein import into isolated mitochondria.

  title={Protein import into isolated mitochondria.},
  author={Dejana Mokranjac and Walter Neupert},
  journal={Methods in molecular biology},
Import of proteins into mitochondria is a pivotal process in the biogenesis of mitochondria. Only about 1% of the 1000-2000 different proteins constituting the mitochondrion are encoded in the mitochondrial deoxyribonucleic acid (DNA). All others are specified by nuclear genes. They are translated in the cytosol and released from ribosomes as precursor proteins, which are then translocated into the various mitochondrial subcompartments. In the past, a variety of methods has been developed to… CONTINUE READING

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