Protein identification from product ion spectra of peptides validated by correlation between measured and predicted elution times in liquid chromatography/mass spectrometry.

@article{Kawakami2005ProteinIF,
  title={Protein identification from product ion spectra of peptides validated by correlation between measured and predicted elution times in liquid chromatography/mass spectrometry.},
  author={Takao Kawakami and Keita Tateishi and Yuko Yamano and Takashi Ishikawa and Kazuyuki Kuroki and Toshihide Nishimura},
  journal={Proteomics},
  year={2005},
  volume={5 4},
  pages={856-64}
}
Reversed-phase liquid chromatography (LC) directly coupled with electrospray-tandem mass spectrometry (MS/MS) is a successful choice to obtain a large number of product ion spectra from a complex peptide mixture. We describe a search validation program, ScoreRidge, developed for analysis of LC-MS/MS data. The program validates peptide assignments to product ion spectra resulting from usual probability-based searches against primary structure databases. The validation is based only on… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Current Awareness on Comparative and Functional Genomics

Comparative and Functional Genomics • 2005

Similar Papers

Loading similar papers…