Protein folding in the cell.

Abstract

In the cell, as in vitro, the final conformation of a protein is determined by its amino-acid sequence. But whereas some isolated proteins can be denatured and refolded in vitro in the absence of other macromolecular cellular components, folding and assembly of polypeptides in vivo involves other proteins, many of which belong to families that have been… (More)

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Cite this paper

@article{Gething1992ProteinFI, title={Protein folding in the cell.}, author={M J Gething and Jessica Sambrook}, journal={Nature}, year={1992}, volume={355 6355}, pages={33-45} }