Protein folding in membranes

  title={Protein folding in membranes},
  author={Sebastian Fiedler and Jana Broecker and Sandro Keller},
  journal={Cellular and Molecular Life Sciences},
Separation of cells and organelles by bilayer membranes is a fundamental principle of life. Cellular membranes contain a baffling variety of proteins, which fulfil vital functions as receptors and signal transducers, channels and transporters, motors and anchors. The vast majority of membrane-bound proteins contain bundles of α-helical transmembrane domains. Understanding how these proteins adopt their native, biologically active structures in the complex milieu of a membrane is therefore a… CONTINUE READING


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