Protein folding: Who chaperones nascent chains in bacteria?

@article{Pfanner1999ProteinFW,
  title={Protein folding: Who chaperones nascent chains in bacteria?},
  author={Nikolaus Pfanner},
  journal={Current Biology},
  year={1999},
  volume={9},
  pages={R720-R724}
}
Important advances in biology often occur when problems that have been controversial and seemingly complex are resolved with surprisingly simple and clear answers. Such has been the case with the problem of how proteins fold inside cells, which has seen a number of controversies and solutions in the past decade. A very recent example of this concerns the physiological functions of two molecular chaperones, trigger factor and DnaK, in protein folding in the cytosol of a bacterial cell. The in… CONTINUE READING

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