Protein fold recognition by sequence threading: tools and assessment techniques.

@article{Miller1996ProteinFR,
  title={Protein fold recognition by sequence threading: tools and assessment techniques.},
  author={Robert T. Miller and David T. Jones and Janet M. Thornton},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={1996},
  volume={10 1},
  pages={171-8}
}
Protein fold recognition has been approached by threading an amino acid sequence onto a library of folds, calculating a sequence-structure compatibility score, and ranking these scores. Due to imperfections in the empirically derived pairwise potential functions and the necessarily heuristic approach to the sequence-structure alignment problem, the method benefits from the assessment of threaded models to evaluate the most probable structures among the list of possible folds. THREADER and… CONTINUE READING

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Parallel a - domains : a new fold in protein structures

  • F. Jumak, M. D. Yoder, R. Pickersgill, J. Jenkins
  • Curr . Opin . Struct . Biol .
  • 1995

Development and application of a three - dimensional description of amino acid environments in protein

  • R. T. Miller, R. J. Douthart, A. K. Dunker
  • Advances in Molecular Bioinformatics
  • 1994

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