Protein families and their evolution-a structural perspective.

@article{Orengo2005ProteinFA,
  title={Protein families and their evolution-a structural perspective.},
  author={C. Orengo and J. Thornton},
  journal={Annual review of biochemistry},
  year={2005},
  volume={74},
  pages={
          867-900
        }
}
We can now assign about two thirds of the sequences from completed genomes to as few as 1400 domain families for which structures are known and thus more ancient evolutionary relationships established. About 200 of these domain families are common to all kingdoms of life and account for nearly 50% of domain structure annotations in the genomes. Some of these domain families have been very extensively duplicated within a genome and combined with different domain partners giving rise to different… Expand
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References

SHOWING 1-10 OF 90 REFERENCES
Domain combinations in archaeal, eubacterial and eukaryotic proteomes.
  • 468
  • PDF
Did evolution leap to create the protein universe?
  • B. Rost
  • Biology, Medicine
  • Current opinion in structural biology
  • 2002
  • 62
  • PDF
Evolution of protein superfamilies and bacterial genome size.
  • 97
A genomic perspective on protein families.
  • 3,322
  • PDF
Structure, function and evolution of multidomain proteins.
  • 331
  • PDF
Protein families and TRIBES in genome sequence space.
  • 141
  • PDF
The geometry of domain combination in proteins.
  • 136
  • PDF
Survey of current protein family databases and their application in comparative, structural and functional genomics.
  • 22
...
1
2
3
4
5
...