Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: influence of astrocyte contact.

@article{Abbruscato1999ProteinEO,
  title={Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: influence of astrocyte contact.},
  author={Thomas J. Abbruscato and Thomas P Davis},
  journal={Brain research},
  year={1999},
  volume={842 2},
  pages={277-86}
}
The blood-brain barrier (BBB) plays a crucial role in protecting the central nervous system (CNS) from any changes in homeostasis brought about by pathological conditions. Cerebrovascular permeability is an important factor in the development of cerebral edema following stroke [M. Plateel, E. Teissier, R. Cecchelli, Hypoxia, dramatically increases the nonspecific transport of blood-borne proteins to the brain. J. Neurochem. 68 (1997) 874-877] and any changes in its function can have detrimental… CONTINUE READING
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