Protein engineering of Acidovorax facilis 72W nitrilase for bioprocess development

@article{Wu2007ProteinEO,
  title={Protein engineering of Acidovorax facilis 72W nitrilase for bioprocess development},
  author={S. Wu and A. Fogiel and K. L. Petrillo and E. C. Hann and L. Mersinger and R. Dicosimo and D. O'keefe and A. Ben-Bassat and M. S. Payne},
  journal={Biotechnology and Bioengineering},
  year={2007},
  volume={97}
}
Hydroxycarboxylic acid monomers can be used to prepare industrially important polymers. Enzymatic production of such hydroxycarboxylic acids is often preferred to chemical production since the reactions are run at ambient temperature, do not require strongly acidic or basic reaction conditions, and produce the desired product with high selectivity at high conversion. However, native enzymes often do not perform desired reactions with the efficiency required for commercial applications. Protein… Expand
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References

SHOWING 1-10 OF 19 REFERENCES
Comparative biology of mesophilic and thermophilic nitrile hydratases.
  • 26
The nitrilase family of CN hydrolysing enzymes – a comparative study
  • 239
...
1
2
...