Protein disulphide-isomerase: a homologue of thioredoxin implicated in the biosynthesis of secretory proteins.

and have a tendency to aggregate, indicating that formation of a second disulphide in the molecule is accompanied by denaturation of the structure. Reduction of oxidized thymus thioredoxin can be achieved by dithiothreitol or by NADPH and thioredoxin reductase representing a possible autocatalytic control mechanism. Another major difference between the… CONTINUE READING