Protein-disulfide isomerase- and protein thiol-dependent dehydroascorbate reduction and ascorbate accumulation in the lumen of the endoplasmic reticulum.

@article{Nardai2001ProteindisulfideIA,
  title={Protein-disulfide isomerase- and protein thiol-dependent dehydroascorbate reduction and ascorbate accumulation in the lumen of the endoplasmic reticulum.},
  author={G{\'a}bor Nardai and Laurence Braun and Mikl{\'o}s Csala and Vikt{\'o}ria Mile and P{\'e}ter Csermely and Angelo Benedetti and J{\^o}zsef Mandl and G{\'a}bor B{\'a}nhegyi},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 12},
  pages={8825-8}
}
The transport and intraluminal reduction of dehydroascorbate was investigated in microsomal vesicles from various tissues. The highest rates of transport and intraluminal isotope accumulation (using radiolabeled compound and a rapid filtration technique) were found in hepatic microsomes. These microsomes contain the highest amount of protein-disulfide isomerase, which is known to have a dehydroascorbate reductase activity. The steady-state level of intraluminal isotope accumulation was more… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 15 references

FEBS Lett

  • M Csala, L Braun, +5 authors G Bá Nhegyi
  • FEBS Lett
  • 1999

Biochem. J

  • F C Ngkeekwong, L L Ng
  • Biochem. J
  • 1997

Mol. Membr. Biol

  • A Gamberucci, P Marcolongo, +5 authors A Benedetti
  • Mol. Membr. Biol
  • 1996

J. Bioenerg. Biomembr

  • W W Wells, D P Xu
  • J. Bioenerg. Biomembr
  • 1994

Nature

  • M J Gething, J Sambrook
  • Nature
  • 1992

Clin. Chim. Acta Arch. Biochem. Biophys

  • A Burchell, R Hume, +6 authors A Benedetti
  • Clin. Chim. Acta Arch. Biochem. Biophys
  • 1988

Biochem. Physiol

  • S Bjelland
  • Biochem. Physiol
  • 1987

Proc. Natl. Acad. Sci. U. S. A

  • Von Zastrow, M Tritton, T R Castle
  • Proc. Natl. Acad. Sci. U. S. A
  • 1986

Diabetologia

  • P T Varandani, M A Nafz
  • Diabetologia
  • 1985

Science

  • A J Daniels, G Dean, O H Viveros, E J Diliberto, Jr
  • Science
  • 1982

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