Protein damage and death by radiation in Escherichia coli and Deinococcus radiodurans.

@article{Kriko2010ProteinDA,
  title={Protein damage and death by radiation in Escherichia coli and Deinococcus radiodurans.},
  author={Anita Kri{\vs}ko and Miroslav Radman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 32},
  pages={14373-7}
}
Deinococcus radiodurans is among a small number of bacterial species that are extremely resistant to ionizing radiation, UV light, toxic chemicals, and desiccation. We measured proteome oxidation (i.e., protein carbonylation, PC) in D. radiodurans as well as in standard and evolved resistant strains of Escherichia coli exposed to ionizing radiation or UVC light and found a consistent correlation with cell killing. The unique quantitative relationship between incurred PC and cell death holds… CONTINUE READING
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