Protein corona formation in bronchoalveolar fluid enhances diesel exhaust nanoparticle uptake and pro-inflammatory responses in macrophages.

@article{Shaw2016ProteinCF,
  title={Protein corona formation in bronchoalveolar fluid enhances diesel exhaust nanoparticle uptake and pro-inflammatory responses in macrophages.},
  author={Catherine A. Shaw and Gysell M Mortimer and Z. John Deng and Edwin S Carter and Shea P Connell and Mark R. Miller and Rodger Duffin and David E. Newby and Patrick W F Hadoke and Rodney F. Minchin},
  journal={Nanotoxicology},
  year={2016},
  volume={10 7},
  pages={981-91}
}
In biological fluids nanoparticles bind a range of molecules, particularly proteins, on their surface. The resulting protein corona influences biological activity and fate of nanoparticle in vivo. Corona composition is often determined by the biological milieu encountered at the entry portal into the body, and, can therefore, depend on the route of exposure… CONTINUE READING