Protein composition of the hepatitis A virus quasi-envelope.

  title={Protein composition of the hepatitis A virus quasi-envelope.},
  author={Kevin L. McKnight and Ling Xie and Olga Gonz{\'a}lez-L{\'o}pez and Efrain E. Rivera-Serrano and Xian Chen and Stanley M Lemon},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={114 25},
The Picornaviridae are a diverse family of RNA viruses including many pathogens of medical and veterinary importance. Classically considered "nonenveloped," recent studies show that some picornaviruses, notably hepatitis A virus (HAV; genus Hepatovirus) and some members of the Enterovirus genus, are released from cells nonlytically in membranous vesicles. To better understand the biogenesis of quasi-enveloped HAV (eHAV) virions, we conducted a quantitative proteomics analysis of eHAV purified… CONTINUE READING
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