Protein changes occurring during storage of platelet concentrates. A two-dimensional gel electrophoretic analysis.

@article{Snyder1987ProteinCO,
  title={Protein changes occurring during storage of platelet concentrates. A two-dimensional gel electrophoretic analysis.},
  author={Edward L. Snyder and Bruce E. Dunn and Carol S. Giometti and Paula A. Napychank and Narendra N. Tandon and Pasquale Ferri and Jochen Hofmann},
  journal={Transfusion},
  year={1987},
  volume={27 4},
  pages={
          335-41
        }
}
The changes in thrombocyte proteins during 22 degrees C storage of platelet concentrates (PC) were studied. To prepare a reference protein "map" of stored PC, platelet samples were taken on days 1, 7, and 21. The platelet proteins were separated by isoelectric focusing (first-dimension) followed by second-dimension polyacrylamide gradient gel electrophoresis with sodium dodecylsulfate (2D). The silver-stained gels were analyzed by computer to obtain a composite map of stored PC proteins. The… CONTINUE READING
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